**4. Conclusion**

96 Hyperthermia

**3.3. Results** 

125.96 ºC, and the ablation zone radius was 92 mm.

Figure 3 shows the temperature distribution in normal adipose-dominated tissue [34]. The reflection coefficient calculated for the frequency at 2.45 GHz was -2.82 dB, the maximum temperature was 116.03 ºC, and the ablation zone radius was 53 mm. The isotherm was considered at 60 ºC because ablation is produced above this temperature [35]. Figure 4 shows the temperature distribution in breast cancer tissue. The reflection coefficient calculated for the frequency at 2.45 GHz was -6.38 dB, the maximum temperature was

**Figure 3.** Temperature distribution of normal adipose-dominated breast tissue at a microwave power output of 10 W. The isotherm at 60 ºC is highlighted. The illustration shows half the plane through the symmetry axis. Vertical axis (z) corresponds to the longitudinal axis of the antenna; horizontal axis (r)

corresponds to radial direction.

In RFA for high temperature hyperthermia therapy in breast cancer several devices from different manufacturers were used in diverse ways for varying periods of time and assorted protocols, therefore exist heterogeneous results. Nevertheless successful cases for were obtained for smaller tumors with a low failures and complication rate. On the other hand the effect of MWA on malignant and normal adipose-dominated tissues of the breast was simulated using an axisymmetric electromagnetic model. This model can analyze the heating patterns using the bioheat equation. The results from computer modeling demonstrated that, effectively, the difference in dielectrical properties and thermal parameters between the malign and normal adipose-dominated tissue could cause the preferential heating on tumor during MWA. Even though electromagnetic high temperature hyperthermia requires further research, it is a promising minimally invasive modality for the local treatment of breast cancer.
