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and Tahsin Murad Aktan

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Edition, 2007;45

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Corresponding Author

 \*

*Deparment of Histology and Embryology, Faculty of Meram Medicine University of Konya* 

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**Author details** 

*Necmettin Erbakan, Turkey* 

London, 2008:1-3.

Gökhan Cüce\*

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**Chapter 2** 

© 2012 Rafea and Souchelnytskyi, licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is

distribution, and reproduction in any medium, provided the original work is properly cited.

© 2012 Rafea and Souchelnytskyi, licensee InTech. This is a paper distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use,

© 2012 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution,

properly cited.

**2. Knowledge analysis and hypotheses induction** 

**Rediscovering Red Blood Cells:** 

Mahmoud Rafea and Serhiy Souchelnytskyi

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/48593

mammals, RBC is a unique cell because:

blood groups determining genes.

**1. Introduction** 

**Revealing Their Dynamic Antigens** 

**Store and Its Role in Health and Disease** 

The only identifiable function of Red Blood Cells (RBC) is the delivery of Oxygen. In

It has a very especial protein: Hemoglobin which plays the role of carrying Oxygen to

 It has a very especial cell membrane which carries a number of blood groups antigens' systems. Their functions include transporting other proteins and molecules into and out of the cell, maintaining cell structure, attaching to other cells and molecules, and participating in chemical reactions [1]. Those systems are genetically controlled with

The work described in this chapter is based on the function carried out by the cell membrane antigens which are transporting other proteins and molecules into and out of the cell. The question is what are those proteins that are transported? In fact, this question identifies the knowledge gap about RBC role in health and disease. In the next section, some hypotheses will be inducted and deduced through analysis of available background knowledge. The experiments that can proof those hypotheses are described in section 3. This is followed by describing a theory about the role of RBC in health and disease based on the proved hypotheses and how we can benefit from this theory in diagnosing and treating of patients.

Basically, when an antigen is introduced into a body, the immune system (IS) does either one of two reactions: immune tolerance (IT) or immune response (IR). IT-reaction is never

and reproduction in any medium, provided the original work is properly cited.

It does not have cellular organelles like any other cells in the body.

tissues and carries back carbon dioxide to lungs.

