**8.5. Glucocorticoids**

Dexamethasone in high doses (8mg/day) decreases the T4 secretion by the thyroid gland, inhibit the peripheral conversion of T4 to T3, and has immunosuppressive effect. Effect on peripheral conversion of T4 to T3 is additive to propylthiouracil. Glucocorticaids are indicated for the treatment of ophthalmopathy, dermopathy and in thyrotoxic crisis.
