**2.1. Historical perspective**

Robert James Graves, an Irish physician, first described 3 females with this disease in 18351 and for his contribution, this disease is known as Graves' disease in most part of the world. Although a similar syndrome was described by Caleb Hiller Parry, a physician from Bath, England, in 1825.2 Carl A. Von Basedow from Germany first described the triad of exophthalmos, goiter and palpitation.3 In most non English speaking European countries the disease is still known as Basedow's disease.
