**24. Peripheral nerve prosthesis**

Prosthesis is made from various forms of utility polysaccharides. The main objective of research is to develop replacement implants that will not be rejected by the body of the recipient and offering the ability to regenerate damaged nerve. Because chitin has high mechanical strength under physiological conditions (low for chitosan) chitin has the potential to be a good nerve guidance channel. Ferier et al, 2005, used this fact and made chitin tubes that could support nerve cell adhesion and neurite outgrowth [153]. In a research related to nerve regeneration, it was shown that rabbits with the crushed common peroneal nerve exhibit better improvement in peripheral nerve regeneration in the presence of chitooligosaccharide. As a result, chito-oligosaccharide can be used as neuroprotective material with an ability to improve injured peripheral nerve regeneration [154].
