**21. Artificial skin**

The preparation of artificial skin by natural materials such as gelatin, pectin, starch, cellulose, alginate, chitin, collagen, polyamino acids, and dextran has been established to enhance the healing process. The structures of these natural materials are analogs of protein and growth factor structures in the human body that may be more relevant for stimulating the appropriate hysiological responses required for cellular regeneration and tissue reconstructing in wounds [146].

Dressing materials based on chitin, chitosan and derivatives are well-known on the market, and are produced mainly in Japan and the US. JEX KK Co produces composite dressings made of synthetic resins, chitosan and materials of collagen and acetylchitiosan. Eisai Co is manufacture of chitin dressings in sponge form (Chitopack C®) or a PET non-woven modified with chitin (Chitopack C®). The Japanese Unitika Co offers a dressing non-woven of chitosan fibres. The American 3M proposes a chitosan gel preparation (Tegasorb®) and a hydrocolloid (Tegaderm®) designed for the healing of extensive internal wounds.ChorioChit sponge is a biological dressing obtained by lyophilisation of human placenta blended with MCCh.
