**4. Acknowledgment**

We gratefully acknowledge all the postgraduates of JiaoTong University engaged in the study for their detailed record.

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Funding

This study was supported by the Foundation of the Sixth People's Hospital, grant no. 0875 (to Y.D.W.), research grants No.044Y06 (to Y.D.W.) from the youth foundation of Shanghai hygiene bureau, and No.30801230 (to Y.D.W.) from the National Natural Science Foundation of China.
