**1. Introduction**

236 Ectopic Pregnancy – Modern Diagnosis and Management

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author reply e22-3.

Corneal ectopic or interstitial ectopic is a pregnancy that implants in the intrauterine portion of fallopian tube. Due to its location, there is an inherit difficulty in the diagnosis and treatment leading to high mortality compared with other ectopic pregnancies.

Transvaginal Ultrasound scan is the most useful diagnostic tool for establishing the diagnosis though serial β-HCG and even laparoscopy are sometimes needed to confirm the diagnosis.

Due to the high risk of rupture with serious or fatal bleeding, there is no role for the expectant management. Surgery is the most common management option. Though traditionally laparotomy is the main surgical intervention, recently increasing number of laparoscopic or even hysteroscopic approach have been used. Injection of Methotrexate locally or systemically has also been used successfully.
