**2.2.3 Proximal tubal disease: tubo-cornual anastomosis**

Case series and cohort studies demonstrated high pregnancy rates following microsurgical tubo-cornual anastomosis (Johnson et al., 2010). A review of eleven case series in women who underwent proximal tubal operations by microsurgery (n = 490) reported a cumulative EP rate of 0% to 12% and a rate of IUP of 22% to 74% concerning to all patients (Posaci et al., 1999). The largest study from 1997 showed an EP rate of 11% and an IUP rate of 74% after a three year follow-up (Dubiusson et al., 1997). Negativ prognostic factors on the pregnancy rate after tubocornual anastomosis are reduced residual length, damaged intramural portion, presence of chronical inflammation and tubal inclusion in the tubal wall, and tubal endometriosis (Posaci et al., 1999).

In our own study with 68 patients, the EP rate was 10.3% (7/68 patients) whereas the IUP rate was 55.9% (38/68 patients) when tubal anastomosis (reversal of sterilization excluded) was performed (Table 2).
