Preface

*"Gel electrophoresis is finding a wide application because its unique separatory power"*  Oliver Smithies

Since the first report about gel electrophoresis, released in 1930, and despite the alternative fractionation technologies that have recently emerged, gel electrophoresis remains the most popular and most powerful technique that provides a perfect fractionation of macromolecules (DNA, RNA and Proteins). Hundreds of techniques could be set according to experimental atmosphere, including various substrates (agarose or polyacrylamide), gel conditions (native or denaturating), buffers (TAE, TBE, etc) and others. This broad variability enabled further progression and development of gel-based fractionation such as isoelectric focusing, zymograms and 2D-PAGE. With wide application ranging from restriction mapping and genetic fingerprinting, to forensic application and co-application with blotting system, there is no doubt that gel electrophoresis made an overwhelming progress in the "*OMICS*" era.

It is my pleasure to introduce the book "Gel Electrophoresis - Advanced Techniques". This book presents a wide research application of this sophisticated technique with wider scope to better cover this popular topic.

> **Sameh Magdeldin**, MVSc, PhD (Physiology), PhD (Proteomics) Senior post doc researcher and Proteomics team leader Medical School, Niigata University, Japan Assistant Professor (Lecturer), Physiology Department Suez Canal University Egypt

**Part 1** 

**Electrophoresis Application in Ecological and** 

**Biotechnological Aspects** 
