**5. Non-destructive analysis of the composition and mixture ratio for textile products based on infrared spectroscopy**

#### **5.1 Background**

90 Infrared Spectroscopy – Life and Biomedical Sciences

curves, and the average blood glucose value is small. In addition, it is considered to over-

The spectra of diabetics as measured by the fourth day and fifth day were substituted in the individual calibration curve of each subject. Table 3 shows the accuracy of predicted blood glucose value and the EGA result. In addition, the scatter diagram of the Clark grid result of each subject is shown in Fig.11. From the EGA result, all data with one exception of subject #4 data are plotted in A and B zone of clinically safety ranges. Improvement of measurement accuracy is better, but, the important in clinical practice is give first aid when the blood glucose value showed abnormal. Therefore, from a good EGA results, this system can be treated as a reasonable measurement method of blood glucose value in diabetics in clinical practice.

> 1 ± 70 50% 50% 0% 0% 0% 2 ± 60 67% 33% 0% 0% 0% 3 ± 49 20% 80% 0% 0% 0% 4 ± 59 45% 45% 0% 10% 0%

To measure simply place a finger on the prism, this system has the advantage of measuring blood glucose value very easily for diabetics in many elderly. In addition, the burden on nurses is reduced, because the patient can measure in their own. Since the measurement time is about 1 minute, it is possible to measure the many patients in a short time. This is a worthwhile part in the clinical practice. When this system is used as a self-monitor blood glucose sensor of diabetic patients, the measurement error is a large. In particular, SEC of the subject #4 was ± 3 mg/dl, but SEP has become extremely large forecast error in ± 59 mg/dl. This cause is considered to the over-fitting, when building a calibration curve as previously described. In PLSR, if the increasing the number of the PLS factor, SEC is a smaller, SEP becomes large. Therefore, it is necessary to construct a standard curve with the optimal

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<sup>A</sup> <sup>E</sup> <sup>B</sup>

E

D

B

A

Reference value (mg/dl)

C

Subject # SEP EGA-Zone

Table 3. The accuracy of predicted blood glucose value and the EGA result

C

ABCDE
