**3. Hodgkin's Lymphoma**

Hodgkin lymphoma is a neoplastic disease of the lymphoid tissue characterized by the present of multinucleated giant cell of B-cell origin, known as Red-Stenberg cell, in background of numerous reactive lymphocyte (Classical, 2009). HL is less common in Asians, especially at the young adult ages. There is incidence variation by age, social class, geographic location in HL. Thus, the comparison of HL rates in Asian and western countries could inform the relative importance of environmental factors and genetic to disease etiology.
