**4.4 Treatment of secondary tic disorders**

Tic disorders secondary to CNS lesions or infection may improve with antipsychotic drug therapy. Tics are not commonly a disabling feature of neurodegenerative diseases such as Huntington's disease and antipsychotics have the potential to worsen overall motor function. In tardive phenomena patients including tics, discontinuation of the offending agent is suggested as first-line treatment and improvement can be attained with use of clonazepam, clozapine, an alpha-2-agonist46 or reintroduction of an antipsychotic47.
