**6.3.3 Nystatin**

It is used in skin and mucosal candidiasis infections (Apak, 1996; Kanmaz, 2010). It resembles to Amphotericin B as structure. It cannot be absorbed via gastrointestinal channels, skin and mucosae. It may have fungicidal or fungistatic effect (Kanmaz, 2010).

*Dose:* Topical: cream or ointment can be used on the affected area every 6 hours. Therapy should be maintained even after symptoms disappear (Kanmaz, 2010).

PO: from 100.000 U/ml solution 2 ml for term infants, 1 ml for preterm ones every 6 hours for each side of mouth. Therapy should be maintained even after symptoms disappear (Kanmaz, 2010).

*Side effects*: Cream or ointment related rash (Kanmaz, 2010).

*Administration Properties:* Oral suspension must be shaken well before use. This suspension includes <1% alcohol, saccharin, 50% sucrose (Kanmaz, 2010).
