**2.5.3 Brain**

Despite the fact that iodine is one of the most important essential elements, the quantitative data on its concentration in the human brain is really scarce. The nature and site of iodine binding in the human brain is still unknown. The results of Andrasi et al. (Andrási et al., 2004) investigations on iodine distribution between the lipid fraction and in the brain tissue without lipid have indicated that its mean contents vary between 910 ± 147 ng/g dry weight and 281 ± 68 ng/g dry weight depending on the brain region (the highest content was found in susbstantia nigra and the lowest in vermis crebelli).
