**4. Reaction in ionic liquid**

Ionic liquids can be suitable media for biocatalytic synthesis because of their enzyme stabilization effect, reusability and negligible vapour pressure (Yang & Pan, 2005). Many enzymes, especially lipases showed higher activity and greater selectivity in ionic liquids than in organic solvents (Jain et al., 2006). The stability of *Candida antarctica* lipase B (CALB) in ionic liquid was found to be higher than in organic solvent (Romero et al., 2005). The main advantages of ionic liquid + enzyme system are milder, lower reaction temperature comparing with conventional chemical synthesis, it needs less energy investment, can be better-controlled, attended with less side-reaction, furthermore the product more readily separable. In this work the purpose was to find a utilization of fusel oil where biolubricants can be manufactured in ionic liquid.

In organic solvents low conversions were achieved, therefore it became necessary to develop a better method, which is energy efficient, able to achieve higher conversion, furthermore environmental friendly, however waste materials may be as natural substrates. Our aim is to optimize the parameters of production, enhance the yield improving the advantages of enzyme+ionic liquid system.
