**2.1 Primary PCI**

Primary PCI was performed in standard fashion. All subjects were treated with oral clopidogral (600 mg) and aspirin (300 mg) in the emergency department. Thirty one patients were treated with an intravenous bolus injection of heparin (50-70 U/Kg) to achieve coagulation time of ≥ 250msec, Fourteen patients were treated before angioplasty with intravenous eptifibatide as 2 boluses of 180ug/kg, ten minutes apart, and a maintenance infusion at a rate of 2ug/kg/min for 24 hours, and 500 units heparin/hour. Coronary angiography and primary PCI were performed subsequently. Bare metal stents were deployed by high-pressure implantation techniques. Low magnification angiogram at either the right 30 º or 90 º lateral projections with prolonged cine was performed to optimize myocardial blush grade (MBG) documentation at the end of the intervention as previously described ( van't Hof et al, 1998). All patients were treated with clopidogrel and aspirin for 12 months after the procedure.

Effects of Eptifibatide on the Microcirculation After Primary Angioplasty in

Fig. 3. Consistent pulsed-wave Doppler sampling of LAD blood velocity

Fig. 4. Pulsed-wave Doppler of LAD blood velocity with dominant, easy to trace diastolic

Fig. 5. Pulsed-wave Doppler of LAD blood velocity with prominent systolic flow

component

Acute ST-Elevation Myocardial Infarction: A Trans-Thoracic Coronary Artery Doppler Study 63
