**2.1 Indications**

Lung transplant is indicated for patients with chronic, end-stage lung disease for whom no effective medical therapy is available (4,5). The primary goal of lung transplantation is to provide a survival benefit. Such benefit can be conferred to patients with advanced pulmonary fibrosis, cystic fibrosis and primary pulmonary hypertension. Reports for emphysema are conflicting and for Eisenmenger's syndrome transplant did not find a survival benefit. However, as lung transplantation is a palliative treatment, improvements in quality of life in addition to survival benefit should be used to assess effectiveness of this therapy.
