**5.2 Result and discussion of the numerical simulation**

Figure 11(a) and 11(b) shows the results of the simulation. As expected the model successfully illustrated on/off or cumulative changing profile of biomarkers depending on the parameters. By solely changing the increasing and decreasing parameters, *a*, *b*, and *c*, the degree of such cumulative effects was able to controlled. Therefore this simple non-linear kinetic model proposed here can be assumed as a basis for the stress induced physiological response in our body. By elaborating this model though a series of experiments targeting on the variety of stressors with different schedule on various biomarkers, the dynamics of human stress reaction pathways, HPA and SAM systems, would be better understood.
