**6.11 Optical Coherence Tomography (OCT)**

OCT is an upcoming technology for non-invasive cross-sectional imaging in biological systems with a great potential for morphological assessment of various tissues. OCT acquires very high-resolution images through the detection of backscattered near infrared light with the potential to identify a wide range of pathologies in-vivo. Clinical applications of OCT are constrained by its limited penetration depth in tissue and miniaturized fiber-optic probes are used to image deeper within the body. (McLaughlin & Sampson 2010)

FBGs with precise Bragg wavelength, narrow spectral bandwidth less than 0.1 nm and high reflectivity are being applied in the OCT systems to calibrate and align the custom-made spectrometer for the spectral-domain optical coherence tomography (SD-OCT) system operating in the 1300-nm wavelength range. The calibration and characterization protocol was presented and investigated very recently. (Eom et al 2011)
