**4.1 Introduction**

Actually radical prostatectomy is accepted as an election treatment in both low and high risk prostate cancer with different evidence level, and even for very high risk prostate cancer. (Table 3)


Table 3.

The goals of RP are to remove the cancer completely with negative surgical margins, minimal blood loss, no serious perioperative complications, and complete recovery of potency and urinary continence. From an oncologic standpoint, obtaining negative surgical margins is paramount. A positive surgical margin has been associated with as much as 4-fold higher risk of biochemical recurrence, even after adjusting for other prognostic factors such as Gleason grade, extracapsular extension, seminal vesicle invasion, and lymph node metastasis. (48) On the same way, there are good results in terms of morbidity and survival when radical
