**10.3 Calcium**

Protective role of calcium is confirmed in different trials. A result from a study claims that regular daily intake of 3 g calcium as supplement reduce the risk of colorectal adenomas relapse 1 year after their removal. This fact is an evidence of protective action of calcium in the early stages of colorectal carcinogenesis (Baron et al., 1999). Another study reported that high calcium intake is associated with vastly lower risk of development of distal CRC, but not proximal CRC (Wu et al., 2002).
