**11. Conclusions**

Adverse drug reactions is a very frequent problem that affects specially the gastrointestinal tract, being GI bleeding the most common adverse drug reaction causing hospital admission. Patients predisposed to suffer ADRs are elderly, women, renal insufficiency, polipharmacy and drug-drug interactions. Drugs used for treat gastrointestinal disease are quite sure but can b e implicated in ADRs as IBPs, imunosupre4ssants used for autoimmune hepatitis or inflammatory bowel disease. Recognition of this problem is increasing in frequency and new drugs can be responsible for new ADRs. Collaboration between clinician, pharmacists and pharmacology specialists is needed.
