**7.3 Inhibition of DAPE**

Substrate analogues of DAP have been used as the basis for the generation of inhibitors of DAPE. These inhibitors take advantage of the anionic character at the α-carbon during the reaction or mimic the planar transition state. The most potent inhibitors are shown in Fig. 19 (Williams et al., 1996).

Fig. 19. Inhibitors of DAPE.
