Contents

#### **Preface XIII**

#### **Part 1 Pharmacodynamic 1**

	- **Part 2 Experimental Study 141**

Contents VII

Chapter 18 **Novel Strategies in Drug-Induced Acute Kidney Injury 381**

José Juan Escobar-Chávez, Isabel Marlen Rodríguez-Cruz

**Desorption/Ionization Imaging Mass Spectrometry 437**

Alberto Lázaro, Sonia Camaño, Blanca Humanes and Alberto Tejedor

**Transdermal Drug Delivery 397**

and Clara Luisa Domínguez-Delgado

Chapter 21 **Closed-Loop Control of Anaesthetic Effect 453** 

**Part 6 Ethnopharmacology and Toxicology 477** 

Santiago Torres, Juan A. Méndez, Héctor Reboso,

**Human Groups Among Regions in the Medicinal Use of Natural Resource: A Case Study in Diadema,** 

**Sources for Obtaining Pharmacological Principles Potentially Active on CNS Through Catalytic,** 

Yanier Nuñez Figueredo, Juan E. Tacoronte Morales, Alicia Lagarto Parra, Olinka Tiomno Tiomnova, Jorge Tobella Sabater and Jorge Leyva Simeon

**in the Expression of Heme Oxygenase-1 as a Cytoprotective Response to Stress 535**

**Extract Against the Neuromuscular Blockade by**  *Bothrops jararacussu* **Snake Venom and Its** 

Yoko Oshima-Franco, Luana de Jesus Reis Rosa, Gleidy Ana Araujo Silva, Jorge Amaral Filho, Magali Glauzer Silva, Patricia Santos Lopes, José Carlos Cogo, Adélia Cristina Oliveira Cintra

Chapter 19 **Chemical and Physical Enhancers for** 

Chapter 20 **Application of Matrix-Assisted Laser** 

José A. Reboso and Ana León

Chapter 22 **The Influence of Displacement by** 

**São Paulo - Brazil 479** Daniel Garcia and Lin Chau Ming

Chapter 23 **Unconventional Raw Natural Sustainable** 

**Ecologically Clean, Processes 519**

Chapter 24 **Elucidating the Role of Biliverdin Reductase** 

Chapter 25 **Antibothropic Action of** *Camellia sinensis*

**Main Toxin, Bothropstoxin-I 569** 

and Maria Alice da Cruz-Höfling

James R. Reed

**Part 5 Diagnostic 435**

Nobuhiro Zaima

#### **Part 3 Pharmacogenetic 177**

	- **Part 4 Clinical Pharmacology 255**

#### **Part 5 Diagnostic 435**

VI Contents

Chapter 8 **Modification of Interleukin-10 with** 

**Part 3 Pharmacogenetic 177**

Bosun Banjoko

Chapter 12 **Pharmacogenetics –** 

Bill J. Duke

Chapter 15 **Pharmacology of Hormone**

Chapter 16 **A Multi-Level Analysis of World** 

Chapter 10 **Future of Pharmacogenetics in** 

**Part 4 Clinical Pharmacology 255** 

Chapter 14 **Pharmacological Neuromodulation in** 

**Autism Spectrum Disorders 283**

Klaas Poelstra and Leonie Beljaars

Chapter 9 **Pharmacogenetics: The Scientific Basis 179**

**Cardiovascular Diseases 207** 

Yumiko Akamine and Tsukasa Uno

Anjana Munshi and Vandana Sharma

Rianne M.F. Van Schie, Talitha I. Verhoef,

Tom Schalekamp, Felix J.M. Van Der Meer, William K. Redekop and Rahber Thariani

Anke-Hilse Maitland-Van Der Zee, Anthonius de Boer,

Chapter 11 **Warfarin Enantiomers Pharmacokinetics by CYP2C19 223**

**A Treatment Strategy for Alcoholism 231** 

Chapter 13 **Pharmacological Approaches to Improve Ageing 257** 

**Replacement Therapy in Menopause 313**  Adela Voican, Bruno Francou, Liliana Novac,

**Scientific Output in Pharmacology 339**

Chapter 17 **Mephedrone-Related Fatalities in the United Kingdom: Contextual, Clinical and Practical Issues 355**  John M. Corkery, Fabrizio Schifano and A. Hamid Ghodse

and Antonio Perianes-Rodríguez

Pedro J. Camello, Cristina Camello-Almaraz and Maria J. Pozo

Nathalie Chabbert-Buffet, Marianne Canonico, Geri Meduri, Marc Lombes, Pierre-Yves Scarabin, Jacques Young, Anne Guiochon-Mantel and Jérôme Bouligand

Carlos Olmeda-Gómez, Ma-Antonia Ovalle-Perandones

**Mannose-6-Phosphate Groups Yields a Liver-Specific Cytokine with Antifibrotic Activity in Rats 161** Heni Rachmawati, Adriana Mattos, Catharina Reker-Smit,

	- **Part 6 Ethnopharmacology and Toxicology 477**
	- **Part 7 Future Applications 625**
