**7. Methylglyoxal, AGEs, oxidative stress and aging**

The damage inflicted by oxidative stress and the formation of intracellular AGEs likely contribute to cellular aging. From this point of view, both increased MG and AGEs would cause accelerated cellular aging. MG would be a double-edged sword because it is a potent inducer of oxidative stress [17, 62, 94, 95], as discussed below, and it is a major precursor of AGEs formation. AGEs also induce oxidative stress.
