**3.1.4 Malformations of the central nervous system (n=11)**

The pH, pO2, SaO2, and bicarbonate concentration are on average significantly lower than those of the control group.

A state of acidemia, often gaseous and metabolic, is present in 5 cases, and a state of hypoxemia in 6 cases.

These anomalies are found in fetuses with hydrocephaly or spina bifida.

Also noted is one case of acidemia (pH of 7.18), associated with hypercapnia (pCO2 of 7.99 kPa), in the presence of microcephaly linked to a cytomegalovirus (CMV) infection.
