**4. Conclusion**

From previous studies, it is suggested that RAAS blockade has a beneficial effect in controlling BP and preventing CVD in DD-CKD patients. However, the choice of the RAAS inhibitor as well as its use in the treatment of DD-CKD patients have to be carefully determined considering the possible adverse effects and potential interactions with other drugs being used in the treatment of DD-CKD patients. Further studies with an adequate sample size and a thorough design are still needed to determine the effect of RAAS blockade on DD-CKD patients.
