**12. Acknowledgment**

This research was supported by Grant numbers M01RR00051, M01RR00069, the General Research Centers Program, National Center for Research Resources (NCRR/NIH; by NCRR/NIH Colorado CTSI Grant number UL1RR025780, by Grant DK34039 form NIH (NIDDK) and by the Zell Family Foundation. The content of this publication are the authors sole responsibility and do not necessarily represent the official NIH views.
