**2. Morphological considerations about MIH**

426 Contemporary Approach to Dental Caries

A B

C D

E F

Fig. 2. A to F – In the same patient, note the presence of asymmetry and the different levels

Lately, MIH is understood as a hypocalcified subtype of enamel defect with reduced mineral content, low residual content of amelogenins and the presence of more than 16 types of proteins in affected teeth, thirteen of which are found in saliva and crevicular fluid (Kojima et al., 2000, Denny et al., 2008) and the three others (hemoglobin, albumin, complement C3) are major components of blood. Moreover, protein composition of MIH

severity of lesions associated to the color opacities in molars and incisors.

enamel varies with severity of enamel defect. (Mangum et al., 2010a)
