**5. Licorice root**

Licorice is the name applied to the roots and stolons of Glycyrrhiza species. Licorice roots extract contains Glycyrrhizol A, a compound that has strong antimicrobial activity against cariogenic bacteria,. Two pilot human studies indicate that a brief application of Licorice roots extract lollipop led to a marked reduction of cariogenic bacteria in oral cavity among most human subjects tested (Hu et al 2011).
