**1. Introduction**

536 A Bird's-Eye View of Veterinary Medicine

Vasudevan, S, Tong, Y, & Steitz, JA. (2007). Switching from repression to activation: MicroRNAs can up-regulate translation. Science, 318(5858), 1931–1934. Williams, AE, Moschos, SA, Perry, MM, Barnes, PJ, & Lindsay, MA. (2007). Maternally

Xue, G, Sakudo, A, Kim, CK, & Onodera, T. (2008). Coordinate regulation of bovine prion

development. Dev. Dyn., 236(2), 572-580.

imprinted microRNAs are differentially expressed during mouse and human lung

protein gene promoter activity by two Sp1 binding site polymorphisms. Xue G, Sakudo A, Kim CK, Onodera T. Biochem Biophys Res. Commun., 372(4), 530-535.

> As non-human primates have similar pathophysiological reactions to humans, experimental data evaluating acute rejection reactions following liver transplantation in rhesus monkeys are clinically significant. However, the success rate and long-term survival rate are low, and post-transplant death is one of the major factors influencing survival in rhesus monkeys undergoing experimental liver transplantation.Non-human primates provide the ideal model for clinical studies of liver transplantation. A large number of factors can influence the establishment of a stable and reproducible non-human primate model. Post-transplant death is a major problem in experimental liver transplantation in rhesus monkeys. This study investigates causes of rhesus monkey death following liver transplantation.
