**5. Acknowledgements**

Work was funded by a BBSRC CASE award and carried out at the Institute of Biotechnology, University of Cambridge, UK. *In vivo* imaging experiments were carried out at the Cancer Institute, University College London, UK. FACS cell sorting was carried out by Arnold Pizzey (UCL Cancer Institute, UCL, London). Manuscript was proof-read by Nigel Appleton (Lumora Ltd).
