**Meet the editor**

Dr Lapota is the US Navy's leading scientist in bioluminescence research activities and developer of bioluminescence measurement systems. He has worked at the Space and Naval Warfare Systems Center, Pacific for 33 years. His academic credentials include a PhD in Biology from University of California, Santa Barbara, an MA in Geography and a BS in Zoology from San Diego State

University. His accomplishments include more than 30 published manuscripts in the open literature, 37 symposia presentations, 22 oceanographic expeditions and 10 US Navy patents in bioluminescence instrumentation. Dr Lapota was also awarded two Exemplary Achievement Awards, and the Outstanding Technology Transfer Professional Award from the Federal Laboratory Consortium, for the Qwiklite 200, from Department of Defense in 2008, at SSC PACIFIC. Dr Lapota is a member of the American Geophysical Union (Ocean Sciences Member, 1981-present) Washington, D.C., American Society of Testing and Materials (Committee E47 - Biological Effects), The Explorers Club, Fellow National (Elected 1989), and the Marine Technology Society.

Contents

**Preface IX** 

David Lapota

David Lapota

**Part 1 Oceanic Measurements of Bioluminescence 1** 

**in Southern California Coastal Waters 3** 

**Chlorophyll, and Their Environmental Correlates** 

**Photosynthetic and Heterotrophic Dinoflagellates** 

**Reporters for Imaging Protein-Protein Interactions** 

**Receptors (7TMRs) Oligomerization by Bioluminescence Resonance Energy Transfer (BRET) Technology 81** 

**and Enumeration of Contaminants: The Milliflex Rapid Microbiology Detection and Enumeration System 99** 

**and Protein Foldings in Living Animals 49** 

Valentina Kubale, Luka Drinovec and Milka Vrecl

**Luciferase for Brighter** *In Vivo* **Imaging 119**  Amit Jathoul, Erica Law, Olga Gandelman, Martin Pule, Laurence Tisi and Jim Murray

Chapter 4 **Quantitative Assessment of Seven Transmembrane** 

Chapter 5 **Use of ATP Bioluminescence for Rapid Detection** 

Renaud Chollet and Sébastien Ribault

**Thermostable** *Photinus pyralis*

Chapter 1 **Long Term Dinoflagellate Bioluminescence,** 

Chapter 2 **Seasonal Changes of Bioluminescence in** 

**at San Clemente Island 27** 

Ramasamy Paulmurugan

Chapter 6 **Development of a pH-Tolerant** 

**Part 2 Bioluminescence Imaging Methods 47** 

Chapter 3 **Bioluminescent Proteins: High Sensitive Optical** 
