**2.10 Statistical analysis**

The cytotoxicity data were calculated as a mean ± S.E. Statistical analysis was performed using Student's t-test or one-way analysis of variance (ANOVA), followed by a Bonferroni multiple comparisons test.

The mitochondrial experiments were performed using three independent experiments with different mitochondrial preparations. The values are expressed as means ± S.E. Means were compared using one-way ANOVA for multiple comparisons, followed by Tukey's test. Statistical significance was set at *p*< 0.05.
