**Tau and Amyloid-β Conformational Change to β-Sheet Structures as Effectors in the Development of Alzheimer's Disease**

Martha A. De Anda-Hernández1\*, Karla I. Lira-De León1\*, Raúl Mena2, Victoria Campos-Peña3 and Marco A. Meraz-Ríos1 *Center of Research and Advanced Studies, CINVESTAV-IPN, 1Molecular Biomedicine Department, CINVESTAV-IPN, 2Physiology, Biophysics and Neurosciences Department, CINVESTAV-IPN, 3Experimental Laboratory of Neurodegenerative Diseases, Neurology and Neurosurgery National Institute (INNN), Mexico* 
