**1. Introduction**

446 Modern Metrology Concerns

Yoo, H.-B., Lim, H.-M., Yang, I., Kim,. S.-K., and Park, S.-R. (2011). Flow cytometric

Zhang, L.K., and Gross, M.L. (2000). Matrix-assisted laser desorption/ionization mass

Zimmermann, B.G., Grill, S., Holzgreve, W., Zhong, X.Y., Jackson, L.G., and Hahn, S. (2008).

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865.

*28*, 1087-1093.

Zaia, J. (2010). Mass spectrometry and glycomics. OMICS *14*, 401-418.

investigation on degradation of macro-DNA by common laboratory manipulations.

spectrometry methods for oligodeoxynucleotides: improvements in matrix, detection limits, quantification, and sequencing. J Am Soc Mass Spectrom *11*, 854-

Digital PCR: a powerful new tool for noninvasive prenatal diagnosis? Prenat Diagn

Metrology is the science of measurement. Although it has been extensively used in the engineering and manufacturing fields for decades, measurement applications in dentistry are a relatively recent development. One of the major differences of measuring objects in dentistry is that the shape of human body parts are "free-form" rather than designed geometrical shapes used in industry.
