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18 patients presented as cured, 2 others were improved, and 2 were lost to follow-up **(Mitterbarger et al, 2008a)**. Other studies have been reported early good results for stem cell

Not only stem cell injection therapy is limited to the field of female SUI, however its usage has been extended to treat males with post-prostatectomy incontinence **(Mitterbarger et al,** 

**group** 

20 women SUI MDSC,

**Carr et al, 2008** 8 women SUI MDSCs 63%

**Herschorn et al, 2010** 29 women SUI MDSC 50% cured

In general, stem cell injection therapy into the middle urethra may restore the contractile response of the striated muscle and rhabdosphincter. Early results were encouraging with no reported serious side effects. Autologous MDSCs and ADSC pure injection therapy may be a promising treatment to restore urethral sphincter function. These promising early clinical results warrant further evaluation to validate results, determine durability and focus

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fibroblasts

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**Clinical study Patients (n) Patient** 

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