**9.2.3 Duloxetin**

Duloxetin is a relative recent drug, which is useful for moderate to severe stress urinary incontinence. It has a good profile with a positive effect since the start of the treatment. Its side effects are infrequent (with mild or moderate severity), and of a short duration. Nowadays it is considered as a good alternative for the surgery of stress urinary incontinence in older females (Robinson & Cardozo, 2010).

#### **9.2.4 Alpha-blockers**

Other interesting type of drug is the group of alpha-blockers, especially in men with storage lower urinary tract symptoms and urgency, however, they should be used with caution in the frailest men due to the hemodynamic adverse effects (Schröder et al, 2009; Verdejo, 2011).

patients.
