**1.5.3 Beta defensins**

The beta defensin have a cysteine connectivity of 1-5 2-4 3-6. They present the consensus sequence of Xn-C-X2-4-G-X1-2-CX3-5CX9-10CX5-6CCXn (Ganz, 2003a) (C=cysteine and G=Glycine). They present a tri dimensional structure of a triple stranded beta sheet. The glycine invariant is also present in alpha defensin. This glycine is necessary for the beta bulge structure to be formed, and the protein is unable to fold if it is replaced by any other natural amino acid (Xie et al., 2005).

*Sus scrofa* beta-defensin 1 SVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK
