**3.1 Isolation and identification of endophytes**

One hundred thirty-one endophytes were isolated from peppertree leaves. Nine endophytes active metabolites producers were identified. These, 2 were identified as *Alternaria* sp., 3 as *Phomopsis* sp., 1 as *Penicillium roseopurpureum*, 1 as a basidiomycete, and 1 as *Streptomyces* sp. One hundred ninety-one endophytes were isolated from leaf fragments of *M. ilicifolia*, belonging to 6 genera of fungi: *Alternaria*, *Phyllosticta*, *Xylaria, Phomopsis, Pestalotiopsis* and *Colletotrichum.* Eighteen actinomycetes were isolated from 4000 samples *Vochysia divergens,* with isolation rates of 0.47%, of these 61.1% (11) were isolated from petiole and 38.9% (07) leaves. Three taxa were identified: *Microbispora* sp. (10 isolates), *Micromonospora* sp. (2 isolates) and *Streptomyces sampsonii* (2 isolates).
