**4. Role of biogenic amines in the olfaction success of honeybee**

Natural selection has shaped the brain to learn to associate cues that predict the occurrence of nutritious food. Sensory input is organized to produce memory traces for food stored for retrieval when animals are hungry so that animals can identify signals associated with nutritional rewards and avoid irrelevant or intoxication signals. Numerous biogenic amines receptors play a significant role in different types of behavior, such as social behavior [7]; among all biogenic amine receptors, dopamine, octopamine and serotonin receptors are considered primary biogenic amine receptors. The biogenic amines (BAs) neurotransmitters are key modulators and perform biological activities in animals, plants and microorganisms, BAs are responsible for executing and regulating the multiple behavioral and physiological activities in the body of honeybees as neurotransmitters, neurohormones and neuromodulators (**Figure 1**).

#### **Figure 1.**

*Schematic diagram of dopamine receptor subtypes.*


*Animal Science Annual Volume 2023*


