**6. Functions of the USH complexes**

The severe and early-onset hearing phenotypes in various USH1 and USH2 mouse models make it relatively easier to decipher the functions of USH complexes in the inner ear than in the retina. The following will focus on the three main cellular processes generally believed to involve the USH complexes. Disruption of these USH functions is thought to be the molecular mechanisms underlying USH.
