Contents

#### **Preface XIII**


#### **Part 2 Diagnostics & Prognostics 133**

Chapter 8 **Validation of Protein Biomarkers to Advance the Management of Autoimmune Disorders 135**  David S. Gibson, Sorcha Finnegan, Stephen Pennington, Ji Qiu, Joshua LaBaer, Madeleine E. Rooney and Mark W. Duncan Contents VII

Chapter 18 **Cellular Based Therapies for** 

Menachem Bitan

Chapter 20 **Thionamides-Related Vasculitis in**

**the Treatment of Multiple Sclerosis 355**  James Crooks, Guang-Xian Zhang and Bruno Gran

**Autoimmune Thyroid Disorders: Review of Current Literature and Case Reports 381** 

Giuseppa Perdichizzi and Domenico Cucinotta

**in Autoimmune Disease and Cancer 395**

Chapter 22 **Myasthenia Gravis: New Insights into the Effect of MuSK** 

Chapter 23 **Vasoactive Neuropeptides in Autoimmune Diseases 455** Ekua W. Brenu, Lotti Tajouri, Donald R. Staines

> **Monitoring Patients with Multiple Sclerosis 477**  Dmitry Kostyushev, Dmitry Gnatenko, Mikhail Paltsev,

> **of Autoimmune and Inflammatory Diseases 491**

Gerardo Álvarez de Cienfuegos and Manuel A. de Pablo

**Antibodies and Acetylcholinesterase Inhibitors 433** 

**Part 4 Pathogenesis & Underlying Mechanisms 393** 

Chapter 21 **The Ectopic Germinal Centre Response** 

Anna Rostedt Punga

David I. Stott and Donna McIntyre

and Sonya M. Marshall-Gradisnik

**of Autoimmune Demyelination and**

Aleksandr Gabibov and Sergey Suchkov

Elena Puertollano, María A. Puertollano,

**Part 5 Other Conceptual Advances & New Insights 515** 

Chapter 24 **Antibody-Proteases in the Pathogenesis** 

Chapter 25 **Role of Fatty Acids in the Resolution**

Chapter 26 **Autoimmune Disorder and Autism 517** Xiaohong Li and Hua Zou

Chapter 27 **Chronobiology of and Chronotherapy for Rheumatoid Arthritis 547**

Hideto To

Chapter 19 **Haematopoietic Cell Transplantation and Immunotherapy** 

**for Autoimmune Diseases in Children and Adults 369** 

Elisabetta L. Romeo, Giuseppina T. Russo, Annalisa Giandalia, Provvidenza Villari, Angela A. Mirto, Mariapaola Cucinotta,

	- **Part 3 Therapeutic Interventions 237**

Chapter 18 **Cellular Based Therapies for the Treatment of Multiple Sclerosis 355**  James Crooks, Guang-Xian Zhang and Bruno Gran

VI Contents

**Part 2 Diagnostics & Prognostics 133** 

Chapter 8 **Validation of Protein Biomarkers to Advance the** 

Chapter 9 **Relevance of Autoantibodies for the Classification** 

Sevindzh Gadzhieva and Mikhail Paltsev

**Technologies to Identify New Serological Biomarkers in Autoimmune Diseases 223**

**Therapies in Autoimmune Diseases 239**

Chapter 13 **The Emerging Role of Monoclonal Antibodies** 

Hiroshi Tanaka and Tadaatsu Imaizumi

**Neurological Autoimmune Disorders 289**

**Function of Neural Cells: Implications in Autoimmune Neurological Disorders 323** Oscar Gonzalez-Perez, Norma A. Moy-Lopez

**Neurological Diseases: Established and Novel Clinical Applications 337** 

Ewa Robak and Tadeusz Robak

Chapter 15 **Recent Advances in the Treatment of** 

Chapter 16 **Synthetic Glucocorticoids Modulate** 

and Jorge Guzman-Muniz

Konstantina G. Yiannopoulou

Chapter 17 **Intravenous Immunoglobulins in** 

Chapter 11 **Application of Novel Quantitative Proteomic**

**Part 3 Therapeutic Interventions 237**

Chapter 12 **Application of Monoclonal Antibody** 

**Management of Autoimmune Disorders 135** David S. Gibson, Sorcha Finnegan, Stephen Pennington,

**and Pathogenesis of Neurological Diseases 163** Simone Mader, Benjamin Obholzer and Markus Reindl

Chapter 10 **Preclinical and Predictive Algorithms in Monitoring Patients** 

Sergey Suchkov, Dmitry Kostyushev, Dmitry Gnatenko,

Ji Qiu, Joshua LaBaer, Madeleine E. Rooney and Mark W. Duncan

**with Autoimmune Diseases and Their Relatives-at-Risks 191**

Soyoung Lee, Satoshi Serada, Minoru Fujimoto and Tetsuji Naka

Adrienn Angyal, Jozsef Prechl, Gyorgy Nagy and Gabriella Sarmay

**in the Treatmentof Systemic Lupus Erythematosus 255**

Jagat R. Kanwar, Bhasker Sriramoju and Rupinder K. Kanwar

Chapter 14 **Treatment of Pediatric-Onset Lupus Nephritis: A New Option of Less Cytotoxic Immunosuppressive Therapy 275**

	- **Part 4 Pathogenesis & Underlying Mechanisms 393**
	- **Part 5 Other Conceptual Advances & New Insights 515**
