**Meet the editor**

Dr. Huang received his initial medical education in China (Shantou, 1977-82). He was later awarded the Li Ka Shing Academic Foundation Scholarship to undertake postgraduate training in the UK (1987-90), and subsequently became engaged in active immunology research and teaching at the Universities of Glasgow (1990-7), Oxford (1997-2000) and Hong Kong (2000-7). He is current-

ly a Senior Lecturer affiliated to the Imperial College London (since 2007). Immunology has been his major field of research, with a focus on immune regulation in autoimmune diseases. His current research focuses on the roles of dendritic cells (DC), regulatory T (Treg) and B (Breg) cells in systemic autoimmunity (lupus). Based on their findings, he and his research group members are trying to understand how the immune system is normally regulated, why dysregulation of which may cause diseases, and whether the so-called "self-reactivity" (autoimmunity) can be alternatively switched on, and then effectively redirected for cancer treatment (anti-tumour immunity).

Contents

**Preface XI** 

**Part 1 Disease Phenotypes 1** 

Chapter 2 **Hashimoto's Thyroiditis in** 

Chapter 3 **Primary Sjögren's Syndrome:** 

Chapter 4 **Changing Spectrum of Chronic** 

and Jacek Musiał

Chapter 7 **Sweet Syndrome 119** 

Chapter 6 **Ocular Myasthenia Analysis of** 

Chapter 1 **Autoimmune Disorders Associated to Type 1** 

**Children and Adolescents 27** 

**and Therapeutic Advances 41**  Christine Delporte, Jason Perret and Muhammad S. Soyfoo

Chapter 5 **Autoimmune-Associated Hemophagocytic** 

Maciej Machaczka, Wojciech Sydor, Małgorzata Rucińska, Marta Szostek

Austin Hake and Henry J. Kaminski

Manuel Ginarte and Jaime Toribio

**Diagnostic and Treatment Options 105** 

Giuseppe d'Annunzio and Chiara Russo, Ramona Tallone and Renata Lorini

**Diabetes Mellitus in Children and Adolescents 3** 

Erkan Sarı, Abdulbaki Karaoglu and Ediz Yeşilkaya

**Current Pathophysiological, Diagnostic** 

**Immune Thrombocytopenic Purpura: New Face for an Old Disease 67**  Indu Sabnani and Patricia Tsang

**Syndrome/Macrophage Activation Syndrome 79** 
