**2. Selection methods of magnetic resonance studies**

#### **2.1 Methods of literature review**

The search of works was performed in different databases. The databases used were Pubmed, PsycINFO, Scopus and Cochrane. There has been no restriction in the years to search or on the type of document sought. The terms used for search were: "pedophilia" and "paedophilia" searched in conjunction with the terms "brain" and "neuroimaging". The search terms were limited to title, abstract and keywords.

#### **2.2 Inclusion criteria**


Magnetic Resonance Techniques in Study of Sexual Stimuli Processing in Paedophilia 79

 Total Brain 1 14.29 Region of Interest 6 85.71

 MR functional 4 57.14 MR Structural 3 42.86

 Experimental 7 100 Others 0 0

Control Group: 7 100

Others (non sex

nucleus accumbens and orbitofrontal cortex (Schiffer et al., 2007).

(24)

(15)

(65)

Table 4. Brief summary of the different sMRI studies in paedophilia.

**3.2 Structural magnetic resonance studies** 

**Authors-year N Groups (n) Sex** 

Schiffer *et al*. (2007) 42 P (18), HC

Schiltz *et al*. (2007) 30 P (15), HC

Cantor *et al*. (2008) 130 P(65), NO

Table 3. Brief description and % of the studies included in the review.

Healthy Control 6 85.71

offenders) 1 14.29

The results of the structural magnetic resonance studies that study regions of interest, as frontal and temporo-limbic structures, showed that paedophiles had a lesser volume of gray matter in the frontostriatal circuits and the ventral striatum, which extended into the

> Hetero and homosexuals

> Hetero and homosexuals

Hetero and

HC = Healthy Controls Group, N = Total Sample, NO = Nonsexual Offenders Group, OFC = Orbitofrontal Cortex, P = Paedophiles Group, ROI = Regions of Interest, TB = Total Brain.

homosexuals sMRI of TB

Brain Study

Technique

Design

Sample

**Number of** 

**studies % of the Review** 

**orientation Study Findings in paedophiles** 

Lesser volume of gray matter in ventral striatum, OFC and cerebellum

Lesser volume of gray matter in subcortical regions (amygdala, hypothalamus and septal regions)

Lesser volume of white matter in parietal and temporal lobes

sMRI of ROI

sMRI of ROI

