**2.5 Drug-induced Hemolytic Anemia**

Haemolytic anemia is a blood condition that occurs primarily when red blood cells are destroyed faster than they can be replaced [32–34]. Red blood cells are normally released from the bone marrow and survive for about 120 days before being cleared by phagocytic cells in the spleen and liver. The process by which immature red blood cells are destroyed is called haemolysis. This haemolysis occurs due to red blood cell defects or abnormal changes in the intravascular environment. Both processes may facilitate drug-induced haemolysis. It can develop rapidly or slowly and can be mild or severe.
