**Part 5**

**Outcome Assessment** 

136 Aortic Valve Surgery

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Saito, Ohtsuka, Motomura, Kotsuka, Takamoto, Takazawa. 2003. Early valvular obliteration of cryopreserved aortic valve allograft. *Jpn J Thorac Cardiovasc Surg*, 51.8.384-386 Shioi, Katagi, Okuno, Mori, Jono, Koyama, Nishizawa. 2002. Induction of bone-type alkaline

Solanes, Rigol, Khabiri, Castella, Ramirez, Roque, Agusti, Roig, Perez-Villa, Segales, Pomar,

Tam, Murphy, Parks, Raviele, Vincent, Strieper, Cuadrado.2001.Saphenous vein homograft:

Tintut, Patel, Parhami, Demer.2000.Tumor necrosis factor-alpha promotes in vitro calcification of vascular cells via the cAMP pathway. *Circulation*, 102.21.2636-2642 Vogt, von Segesser, Jenni, Niederhauser, Genoni, Kunzli, Schneider, Turina.1997.Emergency

Yankah, Pasic, Klose, Siniawski, Weng, Hetzer.2005.Homograft reconstruction of the aortic

Zhao, Green, Frazer, Hogan, O'Brien.1994.Donor-specific immune response after aortic

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stages of transplant vasculopathy. *Cryobiology*, 51.2.130-141

alpha and oncostatin M derived from macrophages. *Circ Res*, 91.1.9-16 Silva, Rodrigues, Santoro, Reis, Alvarez-Leite, Gazzinelli. 2002. Expression of indoleamine

136.1.159-167

868

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*Surg*, 28.1.69-75

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**8** 

*1Uzbekistan 2Russia* 

**Forecasting of the Possible** 

**Outcome of Prosthetics of the** 

**Aortal Valve on Preoperational** 

**Anatomo-Functional Hemodynamics** 

*2E.N.Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Novosibirsk,* 

Prosthetics of the aortal valve is recommended as a standard surgical procedure for the majority of patients with defects of the aortal valve, who need surgical treatment [1]. Being the most simple technically possible to make nowadays, prosthetics of the aortal valve makes 13 % from all operations in case of acquired valve defects [2,3]. The 5-year survival rate without operation makes 50-80 % whereas surgical treatment leads to recovery and survival rate increase even at a serious clinical course of aortal defect [4,5,6]. At present stage of cardiosurgery development there are some methods of estimation of risk of operation [7,8,9]. However indicators under which it would be possible to estimate the forecast of AV prosthetics in the postoperative period are quite poor [10,11]. Available scales of risk estimation sometimes limit an exact prediction of risk or overrate the risk at patients who undergo valve surgery with or without coronary shunting [12,13,14,15]. The estimation of preoperative indicators which characterize the postoperative forecast can be useful for

The aim of the research was to estimate the influence of initial anatomic-functional and hemodynamic indicators when forecasting the nearest results at patients after prosthetics of

To estimate the influence of initial anatomic-functional indicators on the results of AV prosthetics 394 patients who underwent isolated AV prosthetics in 2001-2007 have been examined. Out of 394 people there are 311men and 83women at the age of 10 – 78, middle age is 36,9 ± 1,3 years. In Functional ClassI on New York Heart Association there were 14 (3,6 %) patients, in class II - 42 (10,7 %), in class III - 296 (75,0 %), in class IV - 42 (10,7%). Patients have been divided according to hemodynamic implication of defect into two

**1. Introduction** 

the aortal valve.

preoperative stratification of risk.

**2. Material and methods** 

**and According to Heart Indicators** 

F. F. Turaev1, A. M. Karaskov2 and S. I. Zheleznev2 *1V.Vakhidov Republican Specialized Center for Surgery, Tashkent,* 
