**6.1 Manufacturing industry**

DOE can be used to improve the quality of products, to reduce costs, and to increase efficiency. For example;


*Design of Experiments (DOE): Applications and Benefits in Quality Control and Assurance DOI: http://dx.doi.org/10.5772/intechopen.113987*

## **6.2 Engineering**

DOE is used in engineering to improve the design and performance of products and processes. According to [10] in their research presented 77 cases of quality improvement through practical applications of DOE in Engineering. For example;


## **6.3 Medicine**

DOE is used in medicine for diverse applications. DOE found its applications in medical research and practice, including drug formulation, medical device manufacturing, and radiation therapy. Most of these applications widely demonstrate how DOE can be used to systematically investigate and optimize factors influencing key outcomes in medical applications. Some of the key examples are;

