**6. Conclusion**

In the last decade there has been a surge of interest in the application of clinical microdialysis to neuro-oncology. In this chapter we have reviewed the principles of microdialysis, and systematically appraised studies on the use of the technique to investigate gliomagenesis, the effect of treatment with chemotherapy and radiotherapy, and the potential for administration of drugs with retrograde microdialysis. The utility of the technique lies in its use alongside other methods such as in-vitro, animal and imaging studies.
