**Abstract**

In development, social, and management theories, universities have gained increasing relevance as engines of growth and innovation. Alongside private and public agents, universities engage in a collaborative exploration for a shared knowledge base that is not aimed at immediate exploitation. Building upon the notion of knowledge ecosystem, this chapter focuses on the digital training partnerships between the University of Naples and the global hi-tech players of Apple, Cisco, Deloitte, Capgemini, and other advanced manufacturing groups. Through a case study approach, the analysis explores the complementary and competitive relationships emerging within a knowledge-based value creation process, discussing the sustainability of a university-led innovation policy.

**Keywords:** knowledge ecosystem, university-industry collaborations (UICs), university-led innovation, innovation ecosystem, co-innovation
