**6.3 Uric acid biosensor**

Uric acid biosensor works on electrochemistry. In serum or urine generated by the kidney, uric acid is a naturally occurring antioxidant. It is produced as a byproduct of the body's metabolism of purine nucleotides and their derivatives, and it reacts to various biological changes. Unhealthy bodily fluid concentrations are associated with a variety of medical conditions. Because of this, it's important to frequently evaluate uric acid levels. Clinics routinely utilize high-performance liquid chromatography (HPLC), spectrophotometry, uric acid biosensors, chemiluminescence analysis, and other methods to detect uric acid. The uric acid biosensor has drawn increasing attention due to its advantages of being simple to create, highly sensitive, inexpensive, and selective. It is used for the clinical abnormalities' or diseases' detection [1, 25–27].
