**Abstract**

Microbial and parasitic infections are a significant concern in tertiary care, particularly for patients with compromised immune systems or other underlying medical conditions. In this chapter, we will focus on the diagnosis, treatment, and prevention strategies for microbial and parasitic infections in tertiary care. We will examine the different types of infections that can occur, including bacterial, viral, fungal, and parasitic infections, and the challenges associated with their diagnosis and treatment. We will also discuss the role of antimicrobial stewardship in tertiary care and the importance of appropriate use of antibiotics to prevent the development of antimicrobial resistance. Additionally, we will explore the various prevention strategies, such as vaccination, hand hygiene, and environmental disinfection, that can be used to reduce the risk of infections in tertiary care settings. Overall, this chapter highlights the importance of a proactive approach to managing microbial and parasitic infections in tertiary care, including prompt diagnosis, appropriate treatment, and effective prevention strategies.

**Keywords:** tertiary care, microbial infections, antimicrobial stewardship, multidisciplinary team, patient-centered care
