**5. Multiple functions mediated by Rho GTPases in breast cancer**

Rho GTPases mediate housekeeping aspects of cell biology including cell growth, cell polarity, cell adhesion, membrane trafficking and motility. They function as signaling switches that regulate lipid metabolism, microtubules- and actin-based structures, epithelial cell-junctions, cell cycle and apoptosis regulatory proteins, and transcription factors.
