**6. Big data and machine learning**

The combination of big data and machine learning has enabled data processing and analysis to have a greater opportunity to participate in decision-making in a timely manner. There are many areas of healthcare in which such combinations of algorithmic functions have shown positive results for intervention in this case of chronic diseases and their respective treatments. Among these applications, the following stand out: Intensive care medicine: artificial intelligence in the intensive care unit using big data and machine learning in intensive care medicine. Improved specificity of networked distributed physiological alarms based on a simple deterministic reactive intelligent agent in the intensive care environment, Programmed databases to analyze clinical questions of patient diseases and treatments, and intervention protocols to generate new lines of research [26–28].
