**2.5 National early warning score (NEWS)**

The national early warning score (NEWS) was adapted from MEWS and encompasses all the same variables – temperature, pulse, respiratory rate, systolic blood pressure, AVPU score—while adding oxygen saturation, shown to be a strong independent predictor of mortality [11] and considers the need for respiratory support. It has been validated for use in all admitted patients for predicting deterioration, escalation of care, or death within 24 hours. When compared with thirty-three other EWS, NEWS, based on AUROC (Area Under Receiver Operator Curve), outperformed the others in predicting adverse events and in predicting sepsis prior to onset. The thirty-three EWS compared to NEWS all included the following common variables: heart rate, respiratory rate, systolic blood pressure, temperature, AVPU score for consciousness, oxygen saturation, urine output and age. Each had specific weighted scores and thresholds assigned for triggering specific response [12].

*Developing and Deploying a Sepsis Deterioration Machine Learning Algorithm DOI: http://dx.doi.org/10.5772/intechopen.111557*
