**Acknowledgements**

We thank the anonymous reviewers for their thoughtful comments that greatly improve the quality of the manuscript.

#### **Author contributions**

LW and MU conceived the framework. LW and LYZ provided platform and resources. LW contributed to project administration and student supervision. MU, HY, JJW, JWT contributed to literature review. JWT contributed to the schematic illustration. All the authors wrote and revised the manuscript. All the authors approved the submitted version of the manuscript.

#### **Funding statement**

This research was funded by Guangdong Basic and Applied Basic Research Foundation (Grant No. 2022A1515220023) and Research Foundation for Advanced Talents of Guandong Provincial People's Hospital (Grant No. KY012023293).

### **Conflict of interest**

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
