**Acknowledgements**

We would like to thank Christy Edwards of North Carolina, USA, rescuer of affected Clumber spaniels bred in puppy mills, for her valuable insights and unwavering devotion to this regal breed. Her organization is called Clumber Spaniel Rescues, a Private Breed Rescue.

We also thank James Darley of Buckinghamshire, England, for personal communications, the sharing of his detailed research and historical documentation regarding the Clumber, and his devotion to the rebirth of the Royal Spaniel.

*Founder Effect: Breeding a Dog for the Elderly Gentleman Reveals an Animal Model… DOI: http://dx.doi.org/10.5772/intechopen.113912*

Lastly, we thank Dr. Bryant Freeman, Kansas, USA, for personal communication and the sharing of his detailed historical documentation regarding the Clumber and his devotion to the Clumber Spaniel Club of America with the title of Breed Historian.

Christy, James, and Bryant gave much-appreciated depth to our understanding of the Clumber spaniel and the 250+ year odyssey the breed has taken, leading to the small part that our group played in identifying a genetic cause for disease which is leading to increasing the health of a most Royal and Loyal breed.
