**4.4 Crop rotation**

Crop rotation is also a conventional method use by many farmers on large scale cotton farming areas. But in different cotton farming systems, crop rotation have both negative and positive impacts on biotic stress factors according to the crop selected [10, 108]. To destruct the disease cycle and pest chain, choice of most appropriate crops for rotation purposes is key in integrated disease management (IDM), however, the release of disease suppressive microbes to dominate the disease are yet a challenge due to various factors [109].
