**2.5 Homograft tricuspid valve replacement with large atrium septum defect closure and cryoablation procedure in adult**

A 40-year-old woman was admitted to the Chelyabinsk Regional Clinical Hospital with severe tricuspid regurgitation, large atrial septal defect (ASD), signs of right sided-heart failure, and persistent atrial fibrillation. The patient reported progressive exercise-induced shortness of breath (New York Heart Association functional class III) during the last 6 months after she had documented the first episode of AF.
