**6.1 Topical treatment**

a. Lubricating eye drops belong to the primary management of PUK. They improve the quality of the tear film, reduce discomfort, and when used regularly, preservative-free drops contribute to the washout of inflammatory mediators involved in the process of keratolysis from the ocular surface. The frequency of instillation depends on the severity of the patient's symptoms. Supplementary administration of lubricant ointment formulations, especially overnight, may improve comfort and enhance epithelialization [4, 5].

	- low (e.g., fluorometholone 0.1%, loteprednol etabonate 0.2%, and 0.5%)
	- moderate (e.g., prednisolone sodium phosphate 0.5%, betamethasone 0.1%, and dexamethasone 0.1%)
	- high (e.g., predinosolone acetate 1%).
