**Abstract**

Bacterial keratitis is a disease prevalent in the underdeveloped and developing worlds and is a significant cause of vision-threatening keratitis across the globe. Early and exact diagnosis, accurate treatment, and regular follow-up are key determinants of success in these cases and allow to prevent serious complications and ensure optimal patient outcomes. This chapter provides a comprehensive overview of the causes, symptoms, diagnosis, and management of bacterial keratitis. The importance of accurate diagnosis based on culture of corneal scraping, and smear examinations, as well as with the use of diagnostic tools, such as confocal microscopy is highlighted. Treatment options, including medical treatment and surgical interventions, are discussed in detail. Moreover, the chapter provides insights into the latest research and developments including new treatments. It also highlights the need for ongoing monitoring, regular follow-up, and good compliance between patient and doctor to ensure optimal patient outcomes. The patient must be educated to avoid risk factors. The superficial ulcer usually responds well to medical management, whereas deeper non-resolving ulcers require therapeutic penetrating keratoplasty for globe salvage. Overall, this chapter serves as an important resource for clinicians, researchers, and healthcare professionals, providing valuable information on the diagnosis and management of bacterial keratitis.

**Keywords:** bacterial keratitis, bacterial corneal ulcer, corneal infection, infectious keratitis, medical therapy
