**4. Epidemiology**

The incidence of infectious keratitis following refractive surgery varies according to different studies. A major review reported a frequency of 1 in 1000 for PRK, and 1 in 5000 for LASIK [13, 20]. The higher incidence of infectious keratitis for PKR than for LASIK is evident in multiple studies [15, 19]. On the other hand, there is little evidence and few studies yet on the frequency and treatment of infectious keratitis after SMILE [3, 4, 21].
