**11. Novel PD fluid protoypes**

The introduction of novel osmotic agents, is a promising way to improve the biocompatibility (**Figure 8**).


**Figure 8.** *Novel PD fluid prototypes.*

Other preventive strategies:

Peritoneal resting: especially for high solute transport with Type 1 UF failure because this partially reverses some of the functional alterations of peritoneal transport. De souse et al. [24] found decreased D/P creatinine with increased UF capacity, after 4 weeks of peritoneal resting.
