**3. Clinical indications and contraindications**

CRRT is indicated in severe AKI in hemodynamically unstable patients. Many patients in the hospital have a mild AKI in the setting of acute tubular necrosis, drug induced nephropathy, or pre-renal hypoperfusion, these will require IV fluids and time and, the kidneys will recover. ICU patients tend to have more severe cases of AKI with significant tubular necrosis where fluid resuscitation may not improve the kidney function.

Indications for CRRT [4]:

1.Fluid overload: CRRT can help to remove excess fluid from the body in patients with fluid overload, which can occur because of heart failure, liver failure, or other medical conditions.


Relative contraindications for CRRT:

