**6. Anticoagulation**

CRRT requires anticoagulation to prevent clotting of the extracorporeal circuit, which can lead to circuit failure, decreased filter life, and an increased bleeding risk. There are several different methods of anticoagulation for CRRT [10], including:


The choice of anticoagulant is based on a variety of factors, including the patient's underlying medical conditions, bleeding risk, and the preference and experience of the treating physician.
