**3.2 Carboprost**

Carboprost is used as IM injection in 250 μg doses; can be repeated up to eight such doses (i.e. maximum 2 mg). Side effects are nausea, vomiting, diarrhoea, fever, bronchospasm and hypertension. It is used as a last resort. It should also be used with caution in active hepatic or cardiovascular disease.

### **3.3 Misoprostol**

This prostaglandin analogue can replace oxytocin, if not available. It is used at a dose of 600 μg orally or sublingually in PPH. Diarrhoea, shivering, pyrexia and headache are some of the side effects. The drug is second-line agent when methylergometrine is contraindicated such as in preeclampsia.
